Human CD272 (BTLA) activation kit by CRISPRa

CAT#: GA115811

BTLA CRISPRa kit - CRISPR gene activation of human B and T lymphocyte associated

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BTLA
• Locus ID: 151888
• Kit Components:

  GA115811G1, BTLA gRNA vector 1 in pCas-Guide-CRISPRa

  GA115811G2, BTLA gRNA vector 2 in pCas-Guide-CRISPRa

  GA115811G3, BTLA gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001085357, NM_181780
• Synonyms: BTLA1; CD272
• Summary: This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011]