Human RAET1L activation kit by CRISPRa

CAT#: GA115882

RAET1L CRISPRa kit - CRISPR gene activation of human retinoic acid early transcript 1L

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAET1L
• Locus ID: 154064
• Kit Components:

  GA115882G1, RAET1L gRNA vector 1 in pCas-Guide-CRISPRa

  GA115882G2, RAET1L gRNA vector 2 in pCas-Guide-CRISPRa

  GA115882G3, RAET1L gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_130900
• Synonyms: ULBP6
• Summary: RAET1L belongs to the RAET1 family of major histocompatibility complex (MHC) class I-related genes, which are located within a 180-kb cluster on chromosome 6q24.2-q25.3. The REAT1 genes encode glycoproteins that contain extracellular alpha-1 and alpha-2 domains, but they lack the membrane proximal Ig-like alpha-3 domain. Most RAET1 glycoproteins are anchored to the membrane via glycosylphosphatidylinositol (GPI) linkage (Radosavljevic et al., 2002 [PubMed 11827464]). [supplied by OMIM, Mar 2008]