Human Angiomotin like 1 (AMOTL1) activation kit by CRISPRa

CAT#: GA115900

AMOTL1 CRISPRa kit - CRISPR gene activation of human angiomotin like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AMOTL1
• Locus ID: 154810
• Kit Components:

  GA115900G1, AMOTL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115900G2, AMOTL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115900G3, AMOTL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301007, NM_130847
• Synonyms: JEAP
• Summary: The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]