Human AKAP14 activation kit by CRISPRa

CAT#: GA115973

AKAP14 CRISPRa kit - CRISPR gene activation of human A-kinase anchoring protein 14

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AKAP14
• Locus ID: 158798
• Kit Components:

  GA115973G1, AKAP14 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115973G2, AKAP14 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115973G3, AKAP14 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001008534, NM_001008535, NM_178813
• Synonyms: AKAP28; PRKA14
• Summary: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]