Human DGAT2L4 (AWAT2) activation kit by CRISPRa

CAT#: GA115978

AWAT2 CRISPRa kit - CRISPR gene activation of human acyl-CoA wax alcohol acyltransferase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AWAT2
• Locus ID: 158835
• Kit Components:

  GA115978G1, AWAT2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115978G2, AWAT2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115978G3, AWAT2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001002254
• Synonyms: ARAT; DC4; DGAT2L4; MFAT; WS
• Summary: This gene encodes an enzyme belonging to the diacylglycerol acyltransferase family. This enzyme produces wax esters by the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids. It functions in lipid metabolism in the skin, mostly in undifferentiated peripheral sebocytes. This enzyme may also have acyl-CoA:retinol acyltransferase activities, where it catalyzes the synthesis of diacylglycerols and retinyl esters. [provided by RefSeq, May 2010]