Human CLEC12A activation kit by CRISPRa

CAT#: GA115999

CLEC12A CRISPRa kit - CRISPR gene activation of human C-type lectin domain family 12 member A


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol CLEC12A
Locus ID 160364
Kit Components

GA115999G1, CLEC12A gRNA vector 1 in pCas-Guide-CRISPRa

GA115999G2, CLEC12A gRNA vector 2 in pCas-Guide-CRISPRa

GA115999G3, CLEC12A gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001207010, NM_001300730, NM_138337, NM_201623, NM_201625
Synonyms CD371; CLL-1; CLL1; DCAL-2; MICL
Summary This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.