Human CLEC12A activation kit by CRISPRa

CAT#: GA115999

CLEC12A CRISPRa kit - CRISPR gene activation of human C-type lectin domain family 12 member A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLEC12A
• Locus ID: 160364
• Kit Components:

  GA115999G1, CLEC12A gRNA vector 1 in pCas-Guide-CRISPRa

  GA115999G2, CLEC12A gRNA vector 2 in pCas-Guide-CRISPRa

  GA115999G3, CLEC12A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001207010, NM_001300730, NM_138337, NM_201623, NM_201625
• Synonyms: CD371; CLL-1; CLL1; DCAL-2; MICL
• Summary: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]