Human SPRED1 activation kit by CRISPRa

CAT#: GA116031

SPRED1 CRISPRa kit - CRISPR gene activation of human sprouty related EVH1 domain containing 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SPRED1
• Locus ID: 161742
• Kit Components:

  GA116031G1, SPRED1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116031G2, SPRED1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116031G3, SPRED1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_152594
• Synonyms: hSpred1; NFLS; PPP1R147; spred-1
• Summary: The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008]