Human B3GNT6 activation kit by CRISPRa

CAT#: GA116251

B3GNT6 CRISPRa kit - CRISPR gene activation of human UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: B3GNT6
• Locus ID: 192134
• Kit Components:

  GA116251G1, B3GNT6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116251G2, B3GNT6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116251G3, B3GNT6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_138706
• Synonyms: 3-Gn-T6; B3Gn-T6; beta-1; beta3Gn-T6; BGnT-6
• Summary: The protein encoded by this gene is a beta-1,3-N-acetylglucosaminyltransferase that adds an N-acetylglucosamine moiety to N-acetylgalactosamine-modified serine or threonine. The encoded enzyme is responsible for creating the core 3 structure of O-glycans, which are important components of mucin-type glycoproteins. [provided by RefSeq, Dec 2016]