Human HIGD2A activation kit by CRISPRa

CAT#: GA116252

HIGD2A CRISPRa kit - CRISPR gene activation of human HIG1 hypoxia inducible domain family member 2A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HIGD2A
• Locus ID: 192286
• Kit Components:

  GA116252G1, HIGD2A gRNA vector 1 in pCas-Guide-CRISPRa

  GA116252G2, HIGD2A gRNA vector 2 in pCas-Guide-CRISPRa

  GA116252G3, HIGD2A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_138820
• Synonyms: RCF1b
• Summary: The protein encoded by this gene is a subunit of the cytochrome c oxidase complex (complex IV), which is the terminal enzyme in the mitochondrial respiratory chain. The encoded protein is an inner mitochondrial membrane protein and is a functional ortholog of the yeast respiratory supercomplex factor 1 (Rcf1). In mouse, the orthologous protein enhances cell survival under conditions of hypoxia. [provided by RefSeq, Sep 2016]