Human GGN activation kit by CRISPRa

CAT#: GA116313

GGN CRISPRa kit - CRISPR gene activation of human gametogenetin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GGN
• Locus ID: 199720
• Kit Components:

  GA116313G1, GGN gRNA vector 1 in pCas-Guide-CRISPRa

  GA116313G2, GGN gRNA vector 2 in pCas-Guide-CRISPRa

  GA116313G3, GGN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_152657, NM_182477
• Synonyms: FLJ35713; MGC33369
• Summary: This gene is a germ cell-specific gene that encodes proteins that interact with POG (proliferation of germ cells). Alternatively spliced transcript variants of a similar mouse gene encode at least three different proteins, namely gametogenetin protein 1a, gametogenetin protein 2, and gametogenetin protein 3, which show a perinuclear, cytoplasmic, and nucleolar localization, respectively. These proteins regulate the localization of POG and may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]