Human ALG14 activation kit by CRISPRa

CAT#: GA116321

ALG14 CRISPRa kit - CRISPR gene activation of human ALG14 UDP-N-acetylglucosaminyltransferase subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ALG14
• Locus ID: 199857
• Kit Components:

  GA116321G1, ALG14 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116321G2, ALG14 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116321G3, ALG14 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001305242, NM_144988, NR_131032
• Synonyms: CMS15
• Summary: This gene is a member of the glycosyltransferase 1 family. The encoded protein and ALG13 are thought to be subunits of UDP-GlcNAc transferase, which catalyzes the first two committed steps in endoplasmic reticulum N-linked glycosylation. Mutations in this gene have been linked to congenital myasthenic syndrome (CMSWTA). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]