Human RDM1 activation kit by CRISPRa

CAT#: GA116391

RDM1 CRISPRa kit - CRISPR gene activation of human RAD52 motif containing 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RDM1
• Locus ID: 201299
• Kit Components:

  GA116391G1, RDM1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116391G2, RDM1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116391G3, RDM1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001034836, NM_001163120, NM_001163121, NM_001163122, NM_001163124, NM_001163125, NM_001163130, NM_145654, NR_027996, NR_027997, NR_027998, NR_027999, NR_028000, NM_001330194
• Synonyms: RAD52B
• Summary: This gene encodes a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The protein encoded by this gene contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported. [provided by RefSeq, Jul 2008]