Human OR4C11 activation kit by CRISPRa

CAT#: GA116480

OR4C11 CRISPRa kit - CRISPR gene activation of human olfactory receptor family 4 subfamily C member 11

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: OR4C11
• Locus ID: 219429
• Kit Components:

  GA116480G1, OR4C11 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116480G2, OR4C11 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116480G3, OR4C11 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001004700
• Synonyms: OR4C11P; OR11-136
• Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]