Human MATH5 (ATOH7) activation kit by CRISPRa

CAT#: GA116567

ATOH7 CRISPRa kit - CRISPR gene activation of human atonal bHLH transcription factor 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ATOH7
• Locus ID: 220202
• Kit Components:

  GA116567G1, ATOH7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116567G2, ATOH7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116567G3, ATOH7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_145178
• Synonyms: bHLHa13; Math5; NCRNA; PHPVAR; RNANC
• Summary: This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011]