Human FGD2 activation kit by CRISPRa

CAT#: GA116621

FGD2 CRISPRa kit - CRISPR gene activation of human FYVE, RhoGEF and PH domain containing 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FGD2
• Locus ID: 221472
• Kit Components:

  GA116621G1, FGD2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116621G2, FGD2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116621G3, FGD2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_173558
• Synonyms: ZFYVE4
• Summary: The protein encoded by this gene belongs to a family of guanine nucleotide exchange factors (GEFs) which control cytoskeleton-dependent membrane rearrangements by activating the cell division cycle 42 (CDC42) protein. This gene is expressed in B lymphocytes, macrophages, and dendritic cells. The encoded protein may play a role in leukocyte signaling and vesicle trafficking in antigen-presenting cells in the immune system. [provided by RefSeq, Oct 2016]