Human DEFB119 activation kit by CRISPRa

CAT#: GA116708

DEFB119 CRISPRa kit - CRISPR gene activation of human defensin beta 119

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DEFB119
• Locus ID: 245932
• Kit Components:

  GA116708G1, DEFB119 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116708G2, DEFB119 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116708G3, DEFB119 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271209, NM_153289, NM_153323, NM_173460, NR_073151, NR_073152, NR_073153, NR_126440
• Synonyms: DEFB-19; DEFB-20; DEFB20; DEFB120; ESC42-RELA; ESC42-RELB
• Summary: This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]