Human Epigen (EPGN) activation kit by CRISPRa

CAT#: GA116820

EPGN CRISPRa kit - CRISPR gene activation of human epithelial mitogen

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EPGN
• Locus ID: 255324
• Kit Components:

  GA116820G1, EPGN gRNA vector 1 in pCas-Guide-CRISPRa

  GA116820G2, EPGN gRNA vector 2 in pCas-Guide-CRISPRa

  GA116820G3, EPGN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001013442, NM_001270989, NM_001270990, NM_001270991, NM_001270992, NM_001270993, NR_073114, NR_073117
• Synonyms: ALGV3072; EPG; epigen; PRO9904
• Summary: The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]