Human TAS2R40 activation kit by CRISPRa

CAT#: GA116917

TAS2R40 CRISPRa kit - CRISPR gene activation of human taste 2 receptor member 40

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TAS2R40
• Locus ID: 259286
• Kit Components:

  GA116917G1, TAS2R40 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116917G2, TAS2R40 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116917G3, TAS2R40 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_176882
• Synonyms: GPR60; T2R40; T2R58
• Summary: This gene encodes a member of the bitter taste receptor family which belong to the G protein-coupled receptor superfamily and are predominantly expressed in taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a seven-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered together with eight other taste receptor genes on chromosome 7. A decrease in the expression of this gene is associated with hypogeusia. [provided by RefSeq, Jul 2017]