Human GPR133 (ADGRD1) activation kit by CRISPRa

CAT#: GA117019

ADGRD1 CRISPRa kit - CRISPR gene activation of human adhesion G protein-coupled receptor D1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADGRD1
• Locus ID: 283383
• Kit Components:

  GA117019G1, ADGRD1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117019G2, ADGRD1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117019G3, ADGRD1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001330497, NM_198827
• Synonyms: GPR133; PGR25
• Summary: The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al., 2004 [PubMed 15203201]). [supplied by OMIM, Nov 2010]