Human Laminin (LAMA1) activation kit by CRISPRa

CAT#: GA117107

LAMA1 CRISPRa kit - CRISPR gene activation of human laminin subunit alpha 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LAMA1
• Locus ID: 284217
• Kit Components:

  GA117107G1, LAMA1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117107G2, LAMA1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117107G3, LAMA1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005559
• Synonyms: LAMA; PTBHS; S-LAM-alpha
• Summary: This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014]