Human CYP4A22 activation kit by CRISPRa

CAT#: GA117164

CYP4A22 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 4 subfamily A member 22

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CYP4A22
• Locus ID: 284541
• Kit Components:

  GA117164G1, CYP4A22 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117164G2, CYP4A22 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117164G3, CYP4A22 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001010969, NM_001308102
• Synonyms: cytochrome P450 4A22; cytochrome P450 4A22K; cytochrome P450, family 4, subfamily A, polypeptide 22; OTTHUMP00000009560
• Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]