Human Repulsive Guidance Molecule B (RGMB) activation kit by CRISPRa

CAT#: GA117253

RGMB CRISPRa kit - CRISPR gene activation of human repulsive guidance molecule BMP co-receptor b

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RGMB
• Locus ID: 285704
• Kit Components:

  GA117253G1, RGMB gRNA vector 1 in pCas-Guide-CRISPRa

  GA117253G2, RGMB gRNA vector 2 in pCas-Guide-CRISPRa

  GA117253G3, RGMB gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001012761, NM_173670, NM_001366508, NM_001366509, NM_001366510, NM_001366511
• Synonyms: DRAGON
• Summary: RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]). [supplied by OMIM, Apr 2009]