Human KRTAP20-1 activation kit by CRISPRa

CAT#: GA117355

KRTAP20-1 CRISPRa kit - CRISPR gene activation of human keratin associated protein 20-1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KRTAP20-1
• Locus ID: 337975
• Kit Components:

  GA117355G1, KRTAP20-1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117355G2, KRTAP20-1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117355G3, KRTAP20-1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_181615
• Synonyms: KAP20.1
• Summary: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. [UniProtKB/Swiss-Prot Function]