Human Multicilin (MCIDAS) activation kit by CRISPRa

CAT#: GA117615

MCIDAS CRISPRa kit - CRISPR gene activation of human multiciliate differentiation and DNA synthesis associated cell cycle protein


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol MCIDAS
Locus ID 345643
Kit Components

GA117615G1, MCIDAS gRNA vector 1 in pCas-Guide-CRISPRa

GA117615G2, MCIDAS gRNA vector 2 in pCas-Guide-CRISPRa

GA117615G3, MCIDAS gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001190787
Synonyms IDAS; MCI; MCIN
Summary This gene encodes a member of the geminin family of proteins. The encoded nuclear protein is required for the generation of multiciliated cells in respiratory epithelium. Mutations in this gene cause a rare mucociliary clearance disorder associated with recurring respiratory infections in human patients, known as reduced generation of multiple motile cilia (RGMC). [provided by RefSeq, Sep 2016]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.