Human B7 H6 (NCR3LG1) activation kit by CRISPRa

CAT#: GA117762

NCR3LG1 CRISPRa kit - CRISPR gene activation of human natural killer cell cytotoxicity receptor 3 ligand 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NCR3LG1
• Locus ID: 374383
• Kit Components:

  GA117762G1, NCR3LG1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA117762G2, NCR3LG1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA117762G3, NCR3LG1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001202439, NM_001009913, NR_026750
• Synonyms: B7-H6; B7H6; DKFZp686O24166
• Summary: B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]). [supplied by OMIM, Jan 2011]