Human THEMIS activation kit by CRISPRa

CAT#: GA117886

THEMIS CRISPRa kit - CRISPR gene activation of human thymocyte selection associated

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: THEMIS
• Locus ID: 387357
• Kit Components:

  GA117886G1, THEMIS gRNA vector 1 in pCas-Guide-CRISPRa

  GA117886G2, THEMIS gRNA vector 2 in pCas-Guide-CRISPRa

  GA117886G3, THEMIS gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001010923, NM_001164685, NM_001164687, NM_001318531
• Synonyms: C6orf190; C6orf207; GASP; SPOT; TSEPA
• Summary: This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]