Human HIST2H2BF activation kit by CRISPRa

CAT#: GA118472

HIST2H2BF CRISPRa kit - CRISPR gene activation of human histone cluster 2 H2B family member f

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HIST2H2BF
• Locus ID: 440689
• Kit Components:

  GA118472G1, HIST2H2BF gRNA vector 1 in pCas-Guide-CRISPRa

  GA118472G2, HIST2H2BF gRNA vector 2 in pCas-Guide-CRISPRa

  GA118472G3, HIST2H2BF gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001024599, NM_001161334
• Synonyms: FLJ35099; FLJ56780; FLJ56787; MGC131639
• Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family and is found in a histone cluster on chromosome 1. [provided by RefSeq, Aug 2015]