Human OR10C1 activation kit by CRISPRa

CAT#: GA118542

OR10C1 CRISPRa kit - CRISPR gene activation of human olfactory receptor family 10 subfamily C member 1 (gene/pseudogene)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: OR10C1
• Locus ID: 442194
• Kit Components:

  GA118542G1, OR10C1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA118542G2, OR10C1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA118542G3, OR10C1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013941
• Synonyms: hs6M1-17; OR6-31; OR10C1P; OR10C2
• Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015]