Human XAGE1 (XAGE1E) activation kit by CRISPRa

CAT#: GA118818

XAGE1B CRISPRa kit - CRISPR gene activation of human X antigen family member 1B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: XAGE1B
• Locus ID: 653067
• Kit Components:

  GA118818G1, XAGE1B gRNA vector 1 in pCas-Guide-CRISPRa

  GA118818G2, XAGE1B gRNA vector 2 in pCas-Guide-CRISPRa

  GA118818G3, XAGE1B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001097603, NM_001097604, NM_001097605, NR_033257
• Synonyms: xage-1 p16; X antigen family, member 1E; X antigen family member 1E
• Summary: This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants. [provided by RefSeq, Jan 2010]