Human SFTPA1 activation kit by CRISPRa

CAT#: GA118848

SFTPA1 CRISPRa kit - CRISPR gene activation of human surfactant protein A1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SFTPA1
• Locus ID: 653509
• Kit Components:

  GA118848G1, SFTPA1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA118848G2, SFTPA1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA118848G3, SFTPA1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001093770, NM_001164644, NM_001164645, NM_001164646, NM_001164647, NM_005411
• Synonyms: COLEC4; PSAP; PSP-A; PSPA; SFTP1; SFTPA1B; SP-A; SP-A1; SPA; SPA1
• Summary: This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]