Human CDK11A activation kit by CRISPRa

CAT#: GA118961

CDK11A CRISPRa kit - CRISPR gene activation of human cyclin dependent kinase 11A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDK11A
• Locus ID: 728642
• Kit Components:

  GA118961G1, CDK11A gRNA vector 1 in pCas-Guide-CRISPRa

  GA118961G2, CDK11A gRNA vector 2 in pCas-Guide-CRISPRa

  GA118961G3, CDK11A gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313896, NM_001313982, NM_024011, NM_033529, NR_132739, NR_132740
• Synonyms: CDC2L2; CDC2L3; CDK11-p46; CDK11-p58; CDK11-p110; p58GTA; PITSLRE
• Summary: This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]