Mouse Acads activation kit by CRISPRa

CAT#: GA200016

Acads CRISPRa kit - CRISPR gene activation of mouse acyl-Coenzyme A dehydrogenase, short chain

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Acads
• Locus ID: 11409
• Kit Components:

  GA200016G1, Acads gRNA vector 1 in pCas-Guide-CRISPRa

  GA200016G2, Acads gRNA vector 2 in pCas-Guide-CRISPRa

  GA200016G3, Acads gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007383
• Synonyms: AI196007; Bcd-1; Bcd1; Hdlq8; SCAD
• Summary: This gene encodes a homotetrameric mitochondrial flavoprotein and is a member of the acyl-CoA dehydrogenase family. Members of this family catalyze the first step of fatty acid beta-oxidation, forming a C2-C3 trans-double bond in a FAD-dependent reaction. As beta-oxidation cycles through its four steps, each member of the Acyl-CoA dehydrogenase family works at an optimum fatty acid chain-length. This enzyme has its optimum at C(four)-CoA. In mice, deficiency of this gene has been linked to cold sensitivity and increased high-density lipoprotein levels. [provided by RefSeq, Nov 2012]