Mouse Chrnb1 activation kit by CRISPRa

CAT#: GA200035

Chrnb1 CRISPRa kit - CRISPR gene activation of mouse cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Chrnb1
• Locus ID: 11443
• Kit Components:

  GA200035G1, Chrnb1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200035G2, Chrnb1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200035G3, Chrnb1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009601
• Synonyms: Achr-2; Acrb
• Summary: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. [UniProtKB/Swiss-Prot Function]