Mouse Actb activation kit by CRISPRa

CAT#: GA200043

Actb CRISPRa kit - CRISPR gene activation of mouse actin, beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Actb
• Locus ID: 11461
• Kit Components:

  GA200043G1, Actb gRNA vector 1 in pCas-Guide-CRISPRa

  GA200043G2, Actb gRNA vector 2 in pCas-Guide-CRISPRa

  GA200043G3, Actb gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007393
• Synonyms: Actx; beta-actin; E430023M04Rik
• Summary: This gene encodes a member of the actin family of proteins. Actins are highly conserved proteins that are among the most abundant proteins in eukaryotic cells and are involved in cell motility, structure, and integrity. Localization, stability, and translation of the transcribed mRNA are regulated through the binding of multiple factors to its 3' UTR sequence. Homozygous knockout mice for this gene exhibit embryonic lethality. Numerous pseudogenes of this gene have been identified in the mouse genome. [provided by RefSeq, Sep 2015]