Mouse Actg1 activation kit by CRISPRa

CAT#: GA200045

Actg1 CRISPRa kit - CRISPR gene activation of mouse actin, gamma, cytoplasmic 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Actg1
• Locus ID: 11465
• Kit Components:

  GA200045G1, Actg1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200045G2, Actg1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200045G3, Actg1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313923, NM_009609, NM_013798
• Synonyms: Actg; Actl; AL023024; E51
• Summary: Actins are highly conserved proteins that are involved in various types of cell motility and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta, and gamma, have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]