Mouse Angpt1 activation kit by CRISPRa

CAT#: GA200119

Angpt1 CRISPRa kit - CRISPR gene activation of mouse angiopoietin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Angpt1
• Locus ID: 11600
• Kit Components:

  GA200119G1, Angpt1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200119G2, Angpt1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200119G3, Angpt1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001286062, NM_009640
• Synonyms: 1110046O21Rik; Ang-1; Ang1
• Summary: This gene encodes a secreted glycoprotein that belongs to the angiopoietin family of vascular growth factors. The encoded protein is a ligand in the vascular tyrosine kinase signaling pathway and regulates the formation and stabilization of blood vessels. This protein also functions in striated muscles by promoting proliferation, migration and differentiation of skeletal myoblasts and plays an essential role in the vascular response to tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]