Mouse Ahrr activation kit by CRISPRa

CAT#: GA200134

Ahrr CRISPRa kit - CRISPR gene activation of mouse aryl-hydrocarbon receptor repressor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ahrr
• Locus ID: 11624
• Kit Components:

  GA200134G1, Ahrr gRNA vector 1 in pCas-Guide-CRISPRa

  GA200134G2, Ahrr gRNA vector 2 in pCas-Guide-CRISPRa

  GA200134G3, Ahrr gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001317351, NM_009644
• Synonyms: mKIAA1234
• Summary: This gene encodes a protein that represses aryl hydrocarbon receptor-dependent signaling. The encoded protein competes with the aryl hydrocarbon receptor transcription factor for heterodimerization with the aryl hydrocarbon receptor nuclear translocator protein and binding to xenobiotic response element (XRE) sequence in many genes. This protein is implicated in the regulation of cell growth and differentiation as well as mediating dioxin toxicity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]