Mouse Areg activation kit by CRISPRa

CAT#: GA200263

Areg CRISPRa kit - CRISPR gene activation of mouse amphiregulin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Areg
• Locus ID: 11839
• Kit Components:

  GA200263G1, Areg gRNA vector 1 in pCas-Guide-CRISPRa

  GA200263G2, Areg gRNA vector 2 in pCas-Guide-CRISPRa

  GA200263G3, Areg gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009704
• Synonyms: AR; Mcub; Sdgf
• Summary: This gene encodes a member of the epidermal growth factor (EGF) family and preproprotein that is proteolytically processed to generate a mature protein product. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland development. Homozygous knockout mice for this gene exhibit impaired immune system regulation in the skin and gene expression changes characteristic of chronic liver damage. [provided by RefSeq, Aug 2015]