Mouse Bmp1 activation kit by CRISPRa

CAT#: GA200415

Bmp1 CRISPRa kit - CRISPR gene activation of mouse bone morphogenetic protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Bmp1
• Locus ID: 12153
• Kit Components:

  GA200415G1, Bmp1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200415G2, Bmp1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200415G3, Bmp1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009755, NR_033241, NM_001360021
• Synonyms: Pcp; Tld
• Summary: This gene encodes a metalloproteinase that plays an essential role in the formation of the extracellular matrix and is also able to induce ectopic bone formation. Unlike other bone morphogenetic proteins, the protein encoded by this gene is not closely related to transforming growth factor-beta. This protein plays in role several developmental processes. In humans, mutations in this gene are associated with osteogenesis imperfecta and with increased bone mineral density and multiple recurrent fractures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]