Mouse Casp6 activation kit by CRISPRa

CAT#: GA200539

Casp6 CRISPRa kit - CRISPR gene activation of mouse caspase 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Casp6
• Locus ID: 12368
• Kit Components:

  GA200539G1, Casp6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200539G2, Casp6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200539G3, Casp6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009811
• Synonyms: CASP-6; Mch2
• Summary: This gene encodes a member of the cysteine proteases that plays important roles in regulating apoptosis and neurodegeneration. The encoded protein is involved in the transmission of pain and axonal degeneration. Genetic deletion of this gene in mice results in the delay of axon pruning and protects from axon degeneration. [provided by RefSeq, Apr 2015]