Mouse Cast activation kit by CRISPRa

CAT#: GA200546

Cast CRISPRa kit - CRISPR gene activation of mouse calpastatin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cast
• Locus ID: 12380
• Kit Components:

  GA200546G1, Cast gRNA vector 1 in pCas-Guide-CRISPRa

  GA200546G2, Cast gRNA vector 2 in pCas-Guide-CRISPRa

  GA200546G3, Cast gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301153, NM_001301155, NM_001301156, NM_001301157, NM_001301158, NM_001301160, NM_001301181, NM_009817
• Summary: This gene encodes an inhibitor of the calcium-dependent cysteine protease, calpain. This protein plays roles in multiple processes, including apoptosis, cell cycle regulation, and membrane fusion. Multiple protein isoforms exist which contain unique N-terminal domains, and multiple inhibitory domains that share homology with each other. Some isoforms may be tissue-specific. Two different pseudogenes of this gene are found on chromosome 19. [provided by RefSeq, Jul 2014]