Mouse Cbx4 activation kit by CRISPRa

CAT#: GA200571

Cbx4 CRISPRa kit - CRISPR gene activation of mouse chromobox 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cbx4
• Locus ID: 12418
• Kit Components:

  GA200571G1, Cbx4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200571G2, Cbx4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200571G3, Cbx4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007625
• Synonyms: MPc2; PC2
• Summary: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. [UniProtKB/Swiss-Prot Function]