Mouse Cd86 activation kit by CRISPRa

CAT#: GA200643

Cd86 CRISPRa kit - CRISPR gene activation of mouse CD86 antigen

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cd86
• Locus ID: 12524
• Kit Components:

  GA200643G1, Cd86 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200643G2, Cd86 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200643G3, Cd86 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019388
• Synonyms: B7; B7-2; B7.2; B70; Cd28l2; CLS1; ETC-1; Ly-58; Ly58; MB7; MB7-2; TS/A-2
• Summary: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. [UniProtKB/Swiss-Prot Function]