Mouse Cdh15 activation kit by CRISPRa

CAT#: GA200659

Cdh15 CRISPRa kit - CRISPR gene activation of mouse cadherin 15

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cdh15
• Locus ID: 12555
• Kit Components:

  GA200659G1, Cdh15 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200659G2, Cdh15 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200659G3, Cdh15 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007662
• Synonyms: AI323380; Cdh14; Mcad
• Summary: This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Based on the expression of this gene in skeletal muscle, satellite cells and cerebellum, it was postulated that the encoded protein may be important for muscle development and regeneration. Mice lacking the encoded protein appear normal and display no discernible defects in skeletal musculature. Multiple distinct genes of the cadherin family, including this gene, are found on chromosome 8. [provided by RefSeq, Nov 2015]