Mouse Cln3 activation kit by CRISPRa

CAT#: GA200761

Cln3 CRISPRa kit - CRISPR gene activation of mouse ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cln3
• Locus ID: 12752
• Kit Components:

  GA200761G1, Cln3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200761G2, Cln3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200761G3, Cln3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001146311, NM_001329789, NM_009907
• Synonyms: AI323623
• Summary: This gene encodes a transmembrane protein called battenin that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis genes, cause a number of neurodegenerative diseases collectively known as neuronal ceroid lipofuscinoses, the most common of which is juvenile neuronal ceroid-lipofuscinosis (Batten disease). Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]