Mouse Cnr1 activation kit by CRISPRa

CAT#: GA200793

Cnr1 CRISPRa kit - CRISPR gene activation of mouse cannabinoid receptor 1 (brain)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cnr1
• Locus ID: 12801
• Kit Components:

  GA200793G1, Cnr1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200793G2, Cnr1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200793G3, Cnr1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007726, NM_001355020, NM_001355021, NM_001365881
• Synonyms: CB-R; CB1; CB1R
• Summary: Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. [UniProtKB/Swiss-Prot Function]