Mouse Crhr1 activation kit by CRISPRa

CAT#: GA200873

Crhr1 CRISPRa kit - CRISPR gene activation of mouse corticotropin releasing hormone receptor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Crhr1
• Locus ID: 12921
• Kit Components:

  GA200873G1, Crhr1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200873G2, Crhr1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200873G3, Crhr1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313928, NM_001313929, NM_007762
• Synonyms: CRF1R; CRFR1; Crhr
• Summary: The protein encoded by this gene is a G-protein coupled receptor that binds corticotropin-releasing factor (CRH) and urocortin (UCN) with high affinity. The encoded protein upregulates adenylate cyclase activity and intracellular cAMP levels. This protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response, and obesity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]