Mouse Dgcr6 activation kit by CRISPRa

CAT#: GA201065

Dgcr6 CRISPRa kit - CRISPR gene activation of mouse DiGeorge syndrome critical region gene 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Dgcr6
• Locus ID: 13353
• Kit Components:

  GA201065G1, Dgcr6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201065G2, Dgcr6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201065G3, Dgcr6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001289813, NM_001289814, NM_010047, NR_110380
• Summary: This gene encodes a protein that is similar to the gonadal protein in Drosophila (fruit fly). The encoded protein is thought to play a role in migration of neural crest cells during development. Deletions in the human gene are associated with DiGeorge syndrome (or velocardiofacial syndrome) which has many clinical features including cardiac abnormalities, cleft palate, atypical facial features, hypocalcemia, hypoparathyroidism and defective development or congenital absence of the thymus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]