Mouse Ercc3 activation kit by CRISPRa

CAT#: GA201287

Ercc3 CRISPRa kit - CRISPR gene activation of mouse excision repair cross-complementing rodent repair deficiency, complementation group 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ercc3
• Locus ID: 13872
• Kit Components:

  GA201287G1, Ercc3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201287G2, Ercc3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201287G3, Ercc3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_133658
• Synonyms: BTF2 p89; Ercc-3; XPB
• Summary: ATP-dependent 3'-5' DNA helicase, component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage. [UniProtKB/Swiss-Prot Function]