Mouse Flii activation kit by CRISPRa

CAT#: GA201444

Flii CRISPRa kit - CRISPR gene activation of mouse flightless I actin binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Flii
• Locus ID: 14248
• Kit Components:

  GA201444G1, Flii gRNA vector 1 in pCas-Guide-CRISPRa

  GA201444G2, Flii gRNA vector 2 in pCas-Guide-CRISPRa

  GA201444G3, Flii gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001302207, NM_022009
• Synonyms: 3632430F08Rik; Fliih
• Summary: This gene encodes a protein with gelsolin-like repeats and an N-terminal leucine-rich repeat domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. This protein may act as an actin-remodelling protein as well as a transcriptional coactivator. Homozygous knockout mice show embryonic lethality. This protein may act to regulate wound repair. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]